Jalen Speer had 14 points for Florida A&M (12-15, 10-6 Southwestern Athletic Conference). Dimingus Stevens added 11 points.
Grambling State scored 47 points in the second half, a season high for the team.
Prince Moss had 16 points for the Tigers (11-16, 8-6). Cameron Christon added 14 points and seven rebounds. A'mari McCray had 12 points.
The Rattlers improve to 2-0 against the Tigers for the season. Florida A&M defeated Grambling State 75-66 on Jan. 10.
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