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The Ohio Bobcats (9-4) battle against the Wyoming Cowboys (7-5) in the 2022 Arizona Bowl on Friday afternoon. Ohio owns a 5-8 bowl record, including a three-game win streak. In 2019, the Bobcats beat Nevada 30-21 in the Famous Idaho Potato Bowl. On the opposite side, Wyoming has gone 9-8 in bowl games. They have also won three straight bowl games. The Cowboys knocked off Kent State 52-38 in the Famous Idaho Potato Bowl last year. Ohio quarterback Kurtis Rourke is out with a knee injury. Wyoming has a few key players in the transfer portal, including 1,000-yard rusher Titus Swen

Kickoff from Arizona Stadium in Tucson, Ariz., is set for 5:30 p.m. ET. The Bobcats are 2.5-point favorites in the latest Ohio vs. Wyoming odds, while the over/under for total points is 42. Before finalizing any Wyoming vs. Ohio picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio vs. Wyoming and just locked in its picks and Arizona Bowl 2022 predictions. You can head to SportsLine now to see the model's picks. Now, here are several college football odds and betting lines for Wyoming vs. Ohio:

  • Ohio vs. Wyoming spread: Bobcats -2.5
  • Ohio vs. Wyoming over/under: 42 points
  • Ohio vs. Wyoming money line: Bobcats -150, Cowboys +126
  • OH: Bobcats are 8-1 ATS in their last nine games overall
  • WYO: Cowboys are 4-0 ATS in their last four bowl games
  • Ohio vs. Wyoming picks: See picks at SportsLine

Why Ohio can cover

Senior linebacker Keye Thompson has been a consistent contributor to the Bobcats' defense. Thompson is great at diagnosing the run and quickly collapsing on the ball carrier. The Ohio native leads the team in total tackles (96) with three pass deflections and two fumble recoveries. He recorded double-digit tackles in four of his past seven games. In his last outing, he had 11 total stops and a sack.

Senior safety Alvin Floyd is a talented force in the secondary. Floyd impacts both the run and pass game. The Florida native is third on the team in total tackles (70) with two sacks and five pass deflections. Senior cornerback Zack Sanders makes plays on the ball and is a willing tackler. Sanders is tied for first on the team in interceptions (3) with 61 total tackles. In the MAC Championship, he logged a season-high 10 tackles.

Why Wyoming can cover

The Cowboys have a solid defense, allowing 23.4 points per game with 149.7 yards on the ground. They own a formidable duo at linebacker, headlined by sophomore Easton Gibbs. Gibbs is an instinctive tackling machine who flies all over the field. The California native has a knack for finding the ball, leading the team in total tackles (111) with two sacks.

He recorded double-digit stops in five games, including three straight to end the season. On Nov. 25 against Fresno State, Gibbs finished with 12 tackles. Sophomore Shae Suiaunoa is another enforcer in the middle of the field. Suiaunoa has good play recognition and is able to quickly sniff out the play. The Texas native secured 67 total tackles and 2.5 sacks. He logged at least seven total tackles in three of his last four games. 

How to make Wyoming vs. Ohio picks

SportsLine's model is leaning Over on the total, projecting 47 combined points. The model also says one side of the spread has all the value. You can only see the model's pick at SportsLine.

So who wins Ohio vs. Wyoming? And which side of the spread has all the value? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.