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Perhaps the most anticipated matchup of college football championship weekend comes Friday night when the Oregon Ducks face the Washington Huskies in the 2023 Pac-12 Championship Game. Kickoff is set for 8 p.m. ET from Allegiant Stadium in Las Vegas. The winner will take the final championship banner for the Pac-12 in its current form, with both clubs joining the Big Ten. The current College Football Playoff rankings also suggest the winner of Friday's game is essentially a lock for a playoff berth. The No. 3-ranked Huskies (12-0, 9-0), who won the regular season matchup 36-33 against the Ducks in Week 7, will keep or improve their position with another win over Oregon. Conversely, the Ducks (11-1, 8-1) are practically assured of replacing Washington in the top four if they prevail in the rematch.

The Ducks are 9.5-point favorites and the over/under for total points scored is 65.5 in the latest Oregon vs. Washington odds via SportsLine consensus. Before making any Washington vs. Oregon picks, check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It finished the 2023 regular season a profitable 13-9 on top-rated spread picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Oregon vs. Washington and locked in its picks and CFB predictions. You can visit SportsLine now to see the model's picks. Here are the FBS college football odds and betting lines for Washington vs. Oregon:

  • Oregon vs. Washington point spread: Oregon -9.5
  • Oregon vs. Washington over/under: 65.5 points
  • Oregon vs. Washington money line: Oregon -362, Washington +281
  • WASH: The Huskies are a betting underdog for the first time in the 2023 season
  • ORE: The Ducks have covered the spread in four of their past five games
  • Oregon vs. Washington picks: See picks at SportsLine
  • Oregon vs. Washington live stream: fubo (try for free)

Why Oregon can cover

The Heisman Trophy race has been a tight one all year, with Washington's Michael Penix Jr. in the lead for much of the season. Although Penix has done nothing to diminish his case, Oregon quarterback Bo Nix heads into the weekend as the odds-on favorite because of an astounding run of efficiency. The Auburn transfer was once criticized in his early seasons in the SEC for sometimes reckless decision-making, but the senior has had no such trouble this year with the Ducks. Nix has completed 78.6% of his passes for 3,906 yards and 37 touchdowns against just two interceptions.

What's more, Nix has improved as the season progressed. He has registered double-digit incompletions just twice this season and hasn't done so since the Week 7 loss to Washington. He has thrown for a minimum of 367 yards in each of the past four weeks, with the high mark coming against USC with 412 yards, four touchdowns and no interceptions in the 36-27 victory.

Nix also has notched five of his six rushing touchdowns since Week 7, showing an innate knack for when to use his legs when the coverage calls for it. For the season, he has 159 yards on 47 attempts. See which team to pick here.

Why Washington can cover 

A big part of the reason for Washington's success can be attributed to having a seasoned, experienced core of key players who have grown together through multiple seasons, a rarity in the age of turnstile rosters because of loosened transfer rules and NIL deals.

When coach Kalen DeBoer was hired to replace Jimmy Lake before last season, Penix Jr. had already committed to the program. But it was unclear if the Indiana transfer and other key signees would stay, and many college football analysts predicted Washington would have a difficult transition season. DeBoer persuaded Penix to stay, and the quarterback was influential in getting players such as top receiver Rome Odunze and edge rusher Bralen Trice to stick with the Huskies.

The Huskies now own the second-longest winning streak in FBS at 19 games, second only to Georgia with 29 consecutive victories. "There's so much that I call the bones of the program, the core of who we are, to where we could get to this point," DeBoer told the media this week. See which team to pick here.

How to make Washington vs. Oregon picks

SportsLine's model is leaning Under on the total, projecting 59 total points. It also says one side of the spread hits nearly 60% of the time. You can only get the model's pick at SportsLine

So who wins Oregon vs. Washington, and which side of the spread cashes in nearly 60% of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that's up well over $2,000 on top-rated college football picks since its inception, and find out.