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A Saturday afternoon contest features the Miami Marlins (48-58) heading to Wrigley Field and facing the Chicago Cubs (42-63). Miami has continued its skid with a 2-1 loss to Chicago on Friday. The Marlins are 1-6 over their past seven games. On the other side, the Cubs are hoping to stack another victory after dropping five straight games themselves. Pablo Lopez (7-6, 3.41 ERA) will be starting for the Marlins, while Drew Smyly (3-6, 4.42 ERA) is on the hill for Chicago.

First pitch is set for 2:20 p.m. ET. Caesars Sportsbook lists both teams at -110 (risk $110 to win $100) on the money line in the latest Cubs vs. Marlins odds. The over-under for total runs is set at eight. Before locking in any Cubs vs. Marlins picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters Week 18 on a 20-14 roll on top-rated MLB picks, returning almost $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Cubs vs. Marlins and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Marlins vs. Cubs:

  • Marlins vs. Cubs money line: Chicago -110, Miami -110
  • Marlins vs. Cubs run line: Chicago -1.5 (+185)
  • Marlins vs. Cubs over-under: 8 runs
  • MIA: Marlins are 11-5 in their last 16 road games
  • CHC: Cubs are 5-0 in their last five vs. National League East
  • Marlins vs. Cubs picks: See picks at SportsLine

Why you should back the Cubs

Right fielder Seiya Suzuki is a strong all-around player for Chicago. Suzuki has great eyes and patience at the plate. He rarely goes chasing pitches out of the strike zone. The 27-year-old is also a dependable outfielder with a strong throwing arm. Suzuki is hitting .252, with eight home runs, and 31 RBIs.

Outfielder Rafael Ortega is a good athlete with above-average speed. Ortega's bat speed is solid with good awareness at the plate. The 31-year-old can also be a rangy defender, in part to his speed and agility. He can be a base-stealing threat if he's not accounted for. Ortega is hitting .363 with a double over his past three games. 

Why you should back the Marlins

First baseman Garrett Cooper owns good hitting ability with nice pitch recognition. Cooper can hit for average with a compact swing. The 31-year-old has been a reliable defender, standing tall in the corner (6'5). He's leading the club in batting average (.275) along with seven home runs and 42 RBIs.

Second baseman Joey Wendle is a solid hitter for average with some nice pop in his swing. Wendle consistently plays hard and knows how to get into high pitch counts. The 32-year-old doesn't have much home-run power but can push the ball into gaps. His batting average is .267 with 22 RBIs. Wendle ranks tied for fourth on the team in doubles (13). 

How to make Marlins vs. Cubs picks

SportsLine's model is leaning over on the total, projecting 8.3 combined runs, and it says one side of the money line has all the value. You can only get the MLB model's picks at SportsLine.

So who wins Cubs vs. Marlins? And which side has all the value? Visit SportsLine now to find out which side of you need to jump on, all from the model that has crushed its MLB picks, and find out.