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NFL Week 16 opens with a matchup between teams looking to keep pace in the AFC playoff race when Trevor Lawrence and the Jacksonville Jaguars travel to take on Zach Wilson and the New York Jets on Thursday Night Football. Lawrence is officially listed as questionable with a toe injury and heavy rain is in the TNF weather forecast, which should be factored in when building your NFL DFS lineups and NFL DFS stacks for Jaguars vs. Jets on Thursday night. With weather going to be a factor, should Lawrence and Wilson still be considered a must-start options in your TNF Showdown NFL DFS strategy? Or would it make sense to fade the quarterbacks and build around the running backs, tight ends, and wide receivers in the TNF NFL DFS player pool? Travis Etienne, Zay Jones, Christian KirkEvan Engram, Garrett Wilson, Elijah Moore, Zonovan Knight, and C.J. Uzomah all project to be impact classic and showdown NFL DFS picks for Thursday Night Football. 

Before making any Thursday NFL DFS picks for Jaguars vs. Jets on sites like DraftKings and FanDuel of your own, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor

Kaylor is an NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.

Kaylor has been spot-on all season, hitting on epic NFL DFS picks like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3, 6-106-1, 7-92-1), Amari Cooper (7-101-1, 5-131-1), Nick Chubb (23-113-1, 23-101-2), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4, 10-106), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Derrick Henry (132-2), Jimmy Garoppolo (228-4), Michael Pittman (7-61-1), Christian McCaffrey (26-108-1, 6-30), Kirk Cousins (460-4), Justin Jefferson (12-123-1), J.K. Dobbins (13-125), and Aaron Jones (17-90, 4-36-1). Anyone who has followed his picks is way up.

Now, Kaylor has turned his attention to Jets vs. Jaguars on Thursday Night Football Week 16 and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Jaguars vs. Jets on TNF

One of Kaylor's favorite DFS picks for the New York vs. Jacksonville showdown slate on Week 16 Thursday Night Football is Jaguars running back Travis Etienne. With a torrential downpour expected at MetLife Stadium, both teams could struggle to get anything going through the air. Kaylor believes this could result in a heavy workload for Etienne, who has 917 rushing yards and four touchdowns on 182 carries, and 27 catches for 238 yards through the air in 2022.

"After missing his entire rookie season, Travis Etienne is in the midst of a breakout season for Jacksonville, and is looking every bit like the player he was expected to be coming out of Clemson in 2021. Etienne is coming off an outstanding performance against the Dallas Cowboys where he rushed 19 times for 103 yards and caught two passes for 24 yards. With Trevor Lawrence dinged up and rain in the forecast, I am expecting the Jaguars to lean heavily on the 23-year-old running back on TNF. I am projecting 20-plus total touches and around 125 total yards for Etienne on TNF," Kaylor told SportsLine. You can see the rest of Kaylor's NFL DFS picks here.

How to make NFL DFS lineups for Jets vs. Jaguars on TNF

Kaylor is also targeting another undervalued option that could explode for huge numbers for Thursday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's TNF DFS picks, at SportsLine

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Thursday Night Football? And which under-the-radar DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament in 2022, and find out.