The Los Angeles Lakers will take on the Memphis Grizzlies at 10 p.m. ET on Friday at Arena. The Lakers are 20-25 overall and 11-11 at home, while Memphis is 31-13 overall and 11-10 on the road. This will be the first meeting of the season for these two teams, but the Grizzlies won three of four last season and they split those four head-to-head matchups against the spread.

The Grizzlies have been the more profitable team against the spread this season, with a 22-19-3 mark against the number while the Lakers are 20-23-2. Memphis is favored by 7 points in the latest Lakers vs. Grizzlies odds from Caesars Sportsbook and the over/under is set at 243.5. Before entering any Grizzlies vs. Lakers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 14 of the 2022-23 NBA season on a stunning 45-20 roll on all top-rated NBA picks this season, returning more than $2,200. Anyone following it has seen huge returns.

Now, the model has set its sights on Lakers vs. Grizzlies. You can head to SportsLine to see its picks. Here are several NBA betting lines for Grizzlies vs. Lakers:

  • Lakers vs. Grizzlies spread: Lakers +7
  • Lakers vs. Grizzlies over/under: 243.5 points
  • Lakers vs. Grizzlies money line: Los Angeles +228, Memphis -285
  • Lakers vs. Grizzlies picks: See picks here
Featured Game | Los Angeles Lakers vs. Memphis Grizzlies

What you need to know about the Lakers

Los Angeles was within striking distance but couldn't close the gap on Wednesday as it fell 116-111 to the Sacramento Kings. Small forward LeBron James put forth a good effort for the losing side as he had 32 points and nine assists along with eight rebounds. However, he is listed as questionable for Friday's matchup with an ankle injury. Anthony Davis (foot) remains out for LA while Lonnie Walker IV (knee) and Austin Reaves (hamstring) are also listed as out.

James is 38 now but he's still one of the league's most productive players. He's averaging 29.8 points, 8.4 rebounds and 7.0 assists per game, but the Lakers are still 13th in the Western Conference because they don't shoot the ball well and they don't create second-chance opportunities for themselves. Los Angeles ranks 27th in the NBA in 3-point shooting percentage (33.7) and 26th in offensive rebounding percentage (21.3).

What you need to know about the Grizzlies

Meanwhile, the Cleveland Cavaliers typically have all the answers at home, but on Wednesday the Grizzlies proved too difficult a challenge. Memphis escaped with a 115-114 win off a tip-in by Steven Adams with seconds remaining. The Grizzlies' success was spearheaded by the efforts of shooting guard Desmond Bane, who shot 5-for-8 from downtown and finished with 25 points and point guard Ja Morant, who had 24 points and eight assists.

The Grizzlies enter Friday on an 11-game winning streak and Bane has been a major catalyst since he returned to the lineup. In the six games since he was last held out while recovering from a lengthy absence, Bane is averaging 22.5 points per game and shooting a staggering 60.0% from the 3-point line.

How to make Grizzlies vs. Lakers picks

The model has simulated Lakers vs. Grizzlies 10,000 times and the results are in. We can tell you that the model is leaning Under and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

Who wins Lakers vs. Grizzlies? And which side of the spread hits well over 50% of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks, and find out.