Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | J. HurtsJalen Hurts | G. MinshewGardner Minshew | |
| Running Back | M. SandersMiles Sanders | B. ScottBoston Scott | |
| Wide Receiver | A. BrownA.J. Brown | D. SmithDeVonta Smith | |
| Tight End | D. GoedertDallas Goedert | J. StollJack Stoll | |
| Left Tackle | J. MailataJordan Mailata | A. DillardAndre Dillard | — |
| Left Guard | L. DickersonLandon Dickerson | — | — |
| Center | J. KelceJason Kelce | C. JurgensCam Jurgens | — |
| Right Guard | I. SeumaloIsaac Seumalo | — | — |
| Right Tackle | L. JohnsonLane Johnson | J. DriscollJack Driscoll | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | B. GrahamBrandon Graham | J. RobinsonJanarius Robinson | — |
| Right Defensive End | J. SweatJosh Sweat | R. QuinnRobert Quinn | |
| Left Defensive Tackle | F. CoxFletcher Cox | J. DavisJordan Davis | |
| Right Defensive Tackle | J. HargraveJavon Hargrave | L. JosephLinval Joseph | |
| Strongside Linebacker | H. ReddickHaason Reddick | P. JohnsonPatrick Johnson | |
| Middle Linebacker | T. EdwardsT.J. Edwards | N. DeanNakobe Dean | — |
| Weakside Linebacker | K. WhiteKyzir White | C. EllissChristian Elliss | |
| Right Cornerback | D. SlayDarius Slay | J. ScottJosiah Scott | |
| Left Cornerback | J. BradberryJames Bradberry | A. MaddoxAvonte Maddox | |
| Strong Safety | C. Gardner-JohnsonChauncey Gardner-Johnson | M. EppsMarcus Epps | — |
| Free Safety | R. BlankenshipReed Blankenship | K. WallaceK'Von Wallace | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | B. KernBrett Kern | A. SipossArryn Siposs | — |
| Kicker | J. ElliottJake Elliott | — | — |
| Long Snapper | R. LovatoRick Lovato | — | — |
| Holder | B. KernBrett Kern | — | — |
| Punt Returner | B. CoveyBritain Covey | Q. WatkinsQuez Watkins | |
| Kick Returner | B. ScottBoston Scott | B. CoveyBritain Covey |